If you are animating highly detailed, realistic humanoids, you may want an AI-driven solution that handles subtle facial nuances. The Workflow:

Would you like a ready-to-run Blender Python script that imports Rhubarb JSON and creates shape key keyframes for a typical viseme set?

Limited to 9 basic mouth shapes; lacks nuanced expressions for hyper-realistic characters. 2. FaceForm Retargeter (Formerly Faceware)